Abz-(Asn⁶⁷⁰,Leu⁶⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (669-674)-EDDnp
CAS: 1007306-20-8
Ref. 01-4045326
1mg | 144.00 € | ||
5mg | 549.00 € |
Product Information
- JMV2236
Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It corresponds to the Swedish-mutated (JMV2236) b-amyloid precursor protein (bAPP) sequence targeted by b-secretase BACE (b-site APP-cleaving activity). This FRET substrate is more selectively cleaved by BACE1 and BACE2 than by cathepsin D, a disintegrin and metalloprotease 10 (ADAM10), tumor necrosis a-converting enzyme (TACE), presenilin-1 (PS1), or presenilin-2 (PS2).
Chemical properties
Technical inquiry about: 01-4045326 Abz-(Asn⁶⁷⁰,Leu⁶⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (669-674)-EDDnp
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