Estimated delivery in United States, on Monday 10 Apr 2023
Product Information
Name:
(Lys²²)-Amyloid β-Protein (1-40)
Synonyms:
- Amyloid β-Protein (1-40) Italian Mutation, Amyloid β-Protein (1-40) E22K, [Lys22] β-Amyloid (1-40)
CAS:
Description:
The Italian mutation of b-amyloid 1-40 (E22K) aggregates more rapidly than the wild-type sequence 1-40. It showed increased neurotoxicity, which (according to a solid-phase NMR-study of Masuda et al.) may be due to the salt bridge formed between Lys22 and Asp23 in the minor conformer. As the Arctic, Flemish, and Dutch mutants, the Italian mutant is degraded considerably more slowly than wild-type Ab by neprilysin.
Long term storage:
Notes:
Chemical properties
Molecular weight:
4328.92
Formula:
C195H300N54O56S
Purity:
91.3%
Color/Form:
White Lyophilisate
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 01-4049003 (Lys²²)-Amyloid β-Protein (1-40)
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