Product Information
- Preproapelin (61-77) (human, bovine, mouse, rat)
- 16: PN: WO2006023893 SEQID: 3 claimedsequence
- 61-77-Apelin,prepro-
- 6: PN: WO2007072980 SEQID: 21 claimed protein
- Apelin-17
Apelin-17 is an endogenous ligand of the human orphan G protein-coupled receptor APJ, reported to act as a coreceptor of CD4 for human and simian immunodeficiency viruses. Apelin-17 and apelin-13 represent the predominant molecular forms of apelin present in the whole brain, hypothalamus, and plasma. Like apelin-13, apelin-17 exhibited a high activity on extracellular acidification rate and strongly inhibited forskolin-stimulated cAMP production in CHO cells expressing the human or the rat apelin receptor. The peptide might play a crucial role in the maintenance of body fluid homeostasis by counteracting AVP (arginine vasopressin) actions through inhibition of AVP neuron activity and AVP release.
Chemical properties
Technical inquiry about: 01-4050029 Apelin-17 (human, bovine, mouse, rat)
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