Estimated delivery in United States, on Tuesday 12 Dec 2023
Product Information
Name:
(Pyr³)-Amyloid β-Protein (3-40)
CAS:
Description:
The pyroglutamate-modified amyloid-b peptides derived from Ab40 and Ab42 have gained considerable attention as potential key participants in the pathology of Alzheimer's disease (AD) due to their abundance in AD brain, high aggregation propensity, stability, and cellular toxicity. Ab40 and 42 can be N-terminally truncated by action of cathepsin B. The cyclization of Glu3 is catalyzed by glutaminyl cyclase. Hence, inhibition of these enzymes could be a therapeutic approach to AD.
Brand:
Bachem
Long term storage:
Notes:
Chemical properties
Molecular weight:
4125.68
Formula:
C187H283N51O53S
Purity:
97.3%
Color/Form:
White
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 01-4050043 (Pyr³)-Amyloid β-Protein (3-40)
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