Amyloid β-Protein (1-42)

CAS: 107761-42-2

Ref. 01-4089802

Product Information

• Name: Amyloid β-Protein (1-42)
• Synonyms: Aβ42 sodium salt, Beta-Amyloid Peptide (1-42), Human, Daefrhdsgyevhhqklvffaedvgsnkgaiiglmvggvvia, Amyloid Beta-Peptide (1-42) (Human), Amyloid B-Protein Fragment 1-42, Amyloidb-Peptide(1-42)(human), H-Asp-Ala-Glu-Phe-Arg-His-Asp--Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-OH, H-asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Gly-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Ile-Ala-OH, Abeta 1-42, β-Amyloid(1-42)Human

Description

For a detailed description of Ab 1-42, please see product H-1368. For the preparation of Ab for experimental use, Fezoui et al. (2000) found that solvation of synthetic peptide with sodium hydroxide (Ab·NaOH) followed by lyophilization, produced stocks with superior solubility and fibrillogenesis characteristics. Solubilization of the pretreated material with neutral buffers resulted in a pH transition from ≈10.5 to neutral, avoiding the isoelectric point of Ab (pI≈5.5), at which Ab precipitation and aggregation propensity are maximal.

• Brand: Bachem

Chemical properties

• Molecular weight: 4514.1
• Formula: C₂₀₃H₃₁₁N₅₅O₆₀S
• Purity: 92.1%
• Color/Form: White