Product Information
- Amyloid β-Protein (1-40) L34V
Cerebral amyloid angiopathy (CAA) is a common finding in Alzheimer’s disease in which amyloid-Ab vascular deposits are featured in >80% of the cases. Mutations in the positions 21-23 (e.g. Dutch mutation E22Q) are primarily associated with CAA, although they manifest with strikingly different clinical phenotypes: cerebral hemorrhage or dementia. The Piedmont L34V Ab mutant, located outside this hot spot, shows a similar hemorrhagic phenotype, albeit less aggressive than the widely studied Dutch variant.
Chemical properties
Technical inquiry about: 01-4089805 (Val³⁴)-Amyloid β-Protein (1-40)
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