Product Information
Name:Amyloid β-Protein (4-42)
Synonyms:
- Aβ (4-42)
Brand:Bachem
Description:Aβ 4-42 could be one of the earliest and most prominent Aβ species deposited in AD brain. Sequencing of amyloid plaque cores showed that 64% of the isolated Aβ had a phenylalanine at its N-terminus, and indeed, IP/MS experiments identified Aβ 4-42 as a major Aβ species in AD patients. Additionally, Aβ 4-42 was found to be a component of cotton wool plaques in familial AD patients with the V261I PS1 mutation. Aβ 4-42 was discovered as well in amyloid deposits from vascular dementia and familial Danish dementia patients. These observations indicate that Aβ 4-42 may contribute to the development of multiple CNS diseases.
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Chemical properties
Molecular weight:4198.82
Formula:C191H294N52O53S
Purity:80.3%
Color/Form:White Powder
Technical inquiry about: Amyloid β-Protein (4-42)
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