Estimated delivery in United States, on Monday 6 May 2024
Product Information
Name:
(Ser(PO₃H₂)²⁷³)-Nek11 (268-283)
CAS:
Description:
Depletion of NEK11 prevents proteasome-dependent degradation of CDC25A, both in unperturbed and DNA-damaged cells. In addition, NEK11 directly phosphorylates CDC25A, and CHK1 (checkpoint kinase 1) directly activates NEK11 by phosphorylating it on Ser273. Taken together, NEK11 is an important component of the pathway enforcing the G2/M checkpoint, and genetic mutations in NEK11 may contribute to the development of cancer. These results have been shown by Melixetian and coworkers.
Brand:
Bachem
Long term storage:
Notes:
Chemical properties
Molecular weight:
1848.09
Formula:
C77H135N22O26PS
Purity:
97.5%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 01-4104897 (Ser(PO₃H₂)²⁷³)-Nek11 (268-283)
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
