Product Information
Aggregation of a-synuclein (a-syn) into toxic fibrils is a pathogenic hallmark of Parkinson’s disease (PD). Most early onset mutations are located between residues 46-53. The sequence of a-synuclein (45-54) was used by Cheruvara and coworkers as a template for a peptide library. The authors isolated a 10-residue peptide antagonist that potently inhibits a-synuclein aggregation and associated toxicity at 1:1 stoichiometry.
Chemical properties
Technical inquiry about: 01-4107365 α-Synuclein (45-54) (human)
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