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Covidyte™ TF670

Ref. 01-4152546

100Tests
522.00 €
1000Tests
2,455.00 €
Estimated delivery in United States, on Monday 2 Dec 2024

Product Information

Name:
Covidyte™ TF670
Description:

Covidyte™ TF670 is a peptide substrate that can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide Quencher™ 5 (TQ5) as a quencher and Tide Fluor™ 5 (TF5) as a fluorescent donor on the N-and C-terminals respectively where the fluorescence of TF5 is effectively quenched by TQ5 when the peptide is intact. When the peptide is hydrolyzed by coronavirus proteases, the TF5 fragment generates significantly enhanced fluorescence since its fluorescence is no longer quenched by TQ5. The activity of coronavirus proteases can be effectively monitored by the fluorescence intensity of TF5. Covidyte™ TF670 is a robust high throughput screening tool for searching inhibitors of coronavirus proteases. TQ5-TF5 pair has been proven to an extremely effective FRET pair for developing FRET protease substrates. Comparing to the commonly used EDANS substrates (such as Covidyte™ EN450), the TF670 substrate has much stronger and longer fluorescence that is less interfered by colored compounds that often cause false positive hits.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Bachem
Long term storage:
Notes:

Chemical properties

Molecular weight:
3620.0
Formula:
C71H121N21O22S2dye
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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