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Cortistatin-17 (human)
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Cortistatin-17 (human)

CAS: 189450-19-9

Ref. 01-H-5536

1mg
376.00 €Add to cart
0.5mg
239.00 €Add to cart
Estimated delivery in United States, on Tuesday 7 Dec 2021

Product Information

Name:
Cortistatin-17 (human)
Synonyms:
  • Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys
  • H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-Oh
  • H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys-OH, (Disulfide bond)
  • M.W. 2151.53 C96H139N27O24S3
Description:
Cortistatin-17 shows structural similarities to somatostatin. The peptide binds to all somatostatin receptor subtypes (SSTR) in a similar way as the rat cortistatin. Its inhibitory effects on forskolin-stimulated cAMP production in chinese hamster ovary cells expressing SSTR2-5 are dose dependent but slightly less efficient than that of somatostatin-14. Like the rat cortistatin it has an effect on sleep and wakefulness pattern in rat. It decreases the light slow wave sleep (SWS1) and increases the deep slow wave sleep (SWS2) in a dose dependent manner. Administration of the peptide causes a temporary flattening of cortical and hippocampal electroencephalograms.
Long term storage:
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Chemical properties

Molecular weight:
2149.96484
Formula:
C96H139N27O24S3
Purity:
96.1%
Color/Form:
White Powder
MDL:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
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LQ:

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