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17-(Allylamino)-17-demethoxygeldanamycin, 99%
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Alfa Aesar By Thermo Fisher Scientific logo

17-(Allylamino)-17-demethoxygeldanamycin, 99%

CAS: 75747-14-7

Ref. 02-J66960

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Estimated delivery in United States, on Friday 29 Nov 2024

Product Information

Name:
17-(Allylamino)-17-demethoxygeldanamycin, 99%
Synonyms:
  • tanespimycin
  • (4Z,6E,10E)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • (8R,9R,12R,13S,14R,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • (8S,9S,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • 17-(Allylamino)-17-demethoxygeldanamycin
  • 17-(Allylamino)-17-desmethylgeldanamycin
  • 17-(Allylamino)geldanamycin
  • 17-Allylaminodemethoxygeldanamycin
  • 17-Allylaminogeldanamycin
  • 17-Demethoxy-17-(2-propenylamino)geldanamycin
  • See more synonyms
  • 17-Demethoxy-17-allylaminogeldanamycin
  • 17-N-Allylamino-17-demethoxygeldanamycin
  • 17Aag
  • 2-Azabicyclo[16.3.1]docosane, geldanamycin deriv.
  • A 8476
  • Bms 722782
  • Cp 127374
  • Geldanamycin, 17-demethoxy-17-(2-propenylamino)-
  • Kos 953
  • NSC 330507
  • Tanespimycin
Description:

17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. In addition to its anti-tumor effects, 17-AAG also induces apoptosis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Alfa Aesar By Thermo Fisher Scientific
Long term storage:
Notes:

Chemical properties

Molecular weight:
585.70
Formula:
C31H43N3O8
Purity:
99%
Color/Form:
Red to dark red, Powder
InChI key:
AYUNIORJHRXIBJ-CQFHKJEWSA-N
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
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Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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