N-Ethylmaleimide, 98+%

CAS: 128-53-0

Ref. 02-L00355

Product Information

• Name: N-Ethylmaleimide, 98+%
• Synonyms: N-ethylmaleimide NEM maleic acid N-ethylimide nem (n ethylmaleimide), 1-Ethyl-1H-pyrrole-2,5-dione, 1-Ethyl-2,5-dihydro-1H-pyrrole-2,5-dione, Ethylmaleimide, Maleic acid N-ethylimide, Maleimide, N-ethyl-, N-Ethylmaleimid, N-Ethylmaleimide, N-etilmaleimida, NEM, Nsc 7638
• CAS: 128-53-0

Description

Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 125.13
• Formula: C₆H₇NO₂
• Purity: 98+%
• Color/Form: White to cream or pale yellow, Crystals or powder or crystalline powder and/or lumps/chunks or fused solid
• InChI: InChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
• InChI key: HDFGOPSGAURCEO-UHFFFAOYSA-N
• SMILES: CCN1C(=O)C=CC1=O