2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, 98%

CAS: 105832-38-0

Ref. 02-L13538

Product Information

• Name: 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, 98%
• Synonyms: [(dimethylamino)[(2,5-dioxopyrrolidin-1-yl)oxy]methylidene]dimethylazanium tetrafluoroborate, O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium tetrafluoroborate, TSTU, O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium tetrafluoroborate, 2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate, Tstu, N,N,N,N-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate, 2-Succinimido-1,1,3,3-tetra-methyluronium tetrafluoroborate, N-{(dimethylamino)[(2,5-dioxopyrrolidin-1-yl)oxy]methylidene}-N-methylmethanaminium tetrafluoroborate, O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate, O-(N-Succinimidyl)-1,1,3,3-tetramethyl uranium tetrafluoroborate

Description

2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Brand: Alfa Aesar By Thermo Fisher Scientific

Chemical properties

• Molecular weight: 301.05
• Formula: C₉H₁₆BF₄N₃O₃
• Purity: 98%
• Color/Form: White to pale cream, Crystalline powder or needles
• InChI key: YEBLHMRPZHNTEK-UHFFFAOYSA-N