trans-(1R,2S)-2-Phenylcyclopropan-1-amine

CAS: 155-09-9

Ref. 3D-AAA15509

Product Information

• Name: trans-(1R,2S)-2-Phenylcyclopropan-1-amine
• Synonyms: (+-)-Trans-2-Phenylcyclopropylamine, (1R)-2-phenylcyclopropanamine, (1R,2S)-rel-2-Phenylcyclopropanamine, (RS)-Tranylcypromine, (RS)-trans-2-Phenylcyclopropylamine, 2-Phenylcyclopropanamine, 2-Phenylcyclopropanamine (Trans), Cyclopropanamine, 2-phenyl-, (1R,2S)-rel-, Cyclopropanamine, 2-phenyl-, trans-(.+-.)-, Cyclopropylamine, 2-phenyl-, trans-(.+-.)-, Nsc 80664, Skf 385, Tranilcipromina, Transamine, Tranylcypromin, dl-Tranylcypromine, rel-(1R,2S)-2-Phenylcyclopropanamine, trans-1-Amino-2-phenylcyclopropane, trans-2-Phenyl-1-cyclopropylamine, trans-2-Phenylcyclopropan-1-amine, trans-2-Phenylcyclopropanamine, trans-Phenylcyclopropylamine, trans-SKF 385, trans-dl-2-Phenylcyclopropylamine

Description

Trans-(1R,2S)-2-phenylcyclopropan-1-amine (TCPA) is a drug that inhibits the enzyme monoamine oxidase. It has been shown to inhibit the activity of 5-hydroxytryptamine (5-HT) in various cell types and its concentration. TCPA also affects mitochondrial membrane potential and iron homeostasis pathways. The drug was found to be a potent inhibitor of protein kinases, inhibiting signal transduction pathways in both cell culture and animal models. TCPA is a competitive inhibitor of the enzyme monoamine oxidase type A (MAO-A). It binds reversibly to MAO-A, preventing the breakdown of monoamines such as dopamine, norepinephrine, and serotonin. This inhibition results in increased levels of these neurotransmitters which may lead to neurotoxic effects.

• Brand: Biosynth

Chemical properties

• Molecular weight: 133.09 g/mol
• Formula: C₉H₁₁N
• Purity: Min. 95%