Product Information
7-Aminonaphthalene-2-sulfonic acid (7ANS) is a pharmacological agent that is a tyrosine kinase receptor agonist. It exhibits high affinity for the insulin receptor and other receptors of the tyrosine kinase family, such as vascular endothelial growth factor receptor 2 (VEGFR2). 7ANS has shown to be an effective antidiabetic agent in both animal and human studies. 7ANS also has been shown to inhibit hepatic glucose production, increase glucose uptake by skeletal muscle, and enhance insulin sensitivity. 7ANS stimulates glucose transport activity in cells by binding to the ATP-binding site of sodium channels on the cell membrane, which leads to increased amounts of ATP in the cells. This increased ATP level leads to increased phosphorylation of protein substrates, which are necessary for cellular function. In addition, functionalities such as readout or assay conditions can be altered using this molecule.
Chemical properties
Technical inquiry about: 3D-AAA49444 7-Aminonaphthalene-2-sulfonic acid
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