Chlorthion

CAS: 500-28-7

Ref. 3D-AAA50028

Product Information

• Name: Chlorthion
• Synonyms: 3-Chloro-4-nitrophenyl dimethyl phosphorothioate, Ai3-18861, Bay 22190, Bayer 22/190, Brn 2292513, Caswell No. 201, Chloorthion, Chloorthion [Dutch], Chlorothion, Chlorthion methyl, Chlortion, Chlortion [Czech], Compound 22/190, Dimethyl 3-chloro-4-nitrophenyl thionophosphate, EPA Pesticide Chemical Code 034501, Ent 18,861, Hsdb 979, Methyl chlorothion, Methylchlorothion, Nsc 8927, O,O-Dimethyl O-(3-chloro-4-nitrophenyl) phosphorothioate, O,O-Dimethyl O-(3-chloro-4-nitrophenyl) thiophosphate, O,O-Dimethyl O-(3-chloro-4-nitrophenyl)thionophosphate, O,O-Dimethyl O-4-nitro-3-chlorophenyl thiophosphate, O,O-Dimethyl p-nitro-m-chlorophenyl thiophosphate, O,O-Dimethyl-O-(3-chlor-4-nitrophenyl)-monothiophosphat, O,O-Dimethyl-O-(3-chlor-4-nitrophenyl)-monothiophosphat [German], O,O-Dimethyl-O-(4-nitro-5-chlorphenyl)-thionophosphat, O,O-Dimethyl-O-(4-nitro-5-chlorphenyl)-thionophosphat [German], O,O-Dimethyl-O-3-chlor-4-nitrofenylester kyseliny thiofosforecne, O,O-Dimethyl-O-3-chlor-4-nitrofenylester kyseliny thiofosforecne [Czech], O,O-Dimethyl-O-3-chlor-4-nitrofenyltiofosfat, O,O-Dimethyl-O-3-chlor-4-nitrofenyltiofosfat [Czech], O-(3-Chloor-4-nitro-fenyl)-O,O-dimethyl-monothiofosfaat, O-(3-Chloor-4-nitro-fenyl)-O,O-dimethyl-monothiofosfaat [Dutch], O-(3-Chlor-4-nitro-phenyl)-O,O-dimethyl-monothiophosphat, O-(3-Chlor-4-nitro-phenyl)-O,O-dimethyl-monothiophosphat [German], O-(3-Chloro-4-nitrophenyl) O,O-dimethyl thiophosphate, O-(3-Cloro-4-nitro-fenil)-O,O-dimetil-monotiofosfato, O-(3-Cloro-4-nitro-fenil)-O,O-dimetil-monotiofosfato [Italian], Oms 217, Phenol, 3-chloro-4-nitro-, O-ester with O,O-dimethyl phosphorothioate, Phosphorothioic acid, O-(3-chloro-4-nitrophenyl) O,O-di-Me ester, Phosphorothioic acid, O-(3-chloro-4-nitrophenyl) O,O-dimethyl ester, Thiophosphate de O,O-dimethyle et de O-3-chloro-4-nitrophenyle, Thiophosphate de O,O-dimethyle et de O-3-chloro-4-nitrophenyle [French], p-Nitro-m-chlorophenyl dimethyl thionophosphate, O-(3-Chloro-4-nitrophenyl) O,O-dimethyl phosphorothioate, 4-06-00-01357 (Beilstein Handbook Reference), O-(3-Chloro-4-nitrophenyl) O,O-dimethyl phosphorothioate

Description

Chlorthion is a chemical compound that contains a chlorine atom. It inhibits the production of nitric oxide by binding to the enzyme nitric oxide synthase, which converts arginine to citrulline. Chlorthion is used as a model of the inhibitory effect of organophosphate pesticides on the enzyme acetylcholinesterase. Studies have shown that chlorthion has high resistance in control studies and can be found in higher concentrations in biological samples than other organophosphates. In addition, it has been shown that chlorthion binds to DNA and inhibits protein synthesis by forming covalent bonds with phosphate groups. Chlorthion can be eliminated from the body through reactions with rat liver microsomes or excretion in urine. The elimination rate of chlorthion is relatively fast, with a half-life of about 1 hour. Analytical methods for detecting chlorthion include gas chromatography and liquid chromatography-mass

• Brand: Biosynth

Chemical properties

• Molecular weight: 297.65 g/mol
• Formula: C₈H₉ClNO₅PS
• Purity: Min. 95%