Armepavine

CAS: 524-20-9

Ref. 3D-AAA52420

Product Information

• Name: Armepavine
• Synonyms: (-)-Armepavine, (R)-(-)-Armepavine, 4-(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-phenol, 4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenol, 524-20-9, Alkaloid D, from Evonymuseuropaea, Armepavine (8CI), Evoeuropine, NSC 110381, Phenol, 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-, Phenol, 4-[(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl]-, (R)-, Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-
• CAS: 524-20-9

Description

Armepavine is a bisbenzylisoquinoline alkaloid found in the root of Armelia patens. It has been shown to have anti-diabetic, anti-inflammatory and anticancer properties. Armepavine has also been shown to have synergistic effects with sodium citrate when combined with collagen for the treatment of cervical cancer. The matrix effect of armepavine on cervical cancer cells was investigated using a solid phase microextraction technique which showed that armepavine inhibits the proliferation of cervical cancer cells by inducing apoptosis. This may be due to its ability to inhibit the production of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter that inhibits nerve transmission.

• Brand: Biosynth

Chemical properties

• Molecular weight: 313.39 g/mol
• Formula: C₁₉H₂₃NO₃
• Purity: Min. 95%