Cefotaxime

CAS: 63527-52-6

Ref. 3D-AC37153

Product Information

• Name: Cefotaxime
• Synonyms: (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)-acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2, (((2-amino- 4-thiazolyl)methoxyimino)acetyl)amino)-8-oxo-, (6r-(6alpha,7beta(z) 3-[(Acetyloxy)methyl]-7-[[(2-amino-4-thiazoly)(methoxyimino)acethyl]amino]-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylic acid(sodium salt), (6R,7R)-3-[(Acetyl-oxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-[(Acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2-amino-1,3-thiazol-4-yl)(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6S,7S)-3-[(acetyloxy)methyl]-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, [6R-[6α,7α(Z)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, [6R-[6α,7β(Z)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-, Betaksim, C-Tax, Cefabol, Cefotaxim, Cefotaxima, Cefotaxima acid, Cefotaxime acid, Ceftax, Cephotaxime, Claforan, Hexime, Omnatax, Taxim, Zeefotax, sodium (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• CAS: 63527-52-6

Description

Cefotaxime is a β-lactam antibiotic that inhibits the synthesis of bacterial cell walls. It binds to penicillin-binding proteins in the bacterial cell wall by competitive inhibition. Cefotaxime has been shown to be effective against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae. It also has strong antibacterial activity against gram negative species such as Klebsiella pneumoniae and Escherichia coli. Cefotaxime is used for the treatment of various types of bowel diseases, such as colitis due to Clostridium difficile. The mechanism behind its therapeutic effects may be related to its ability to inhibit bacterial growth in the gut by reducing the amount of hydrogen produced by gram negative bacteria (due to cefotaxime's interference with electron transport).

• Brand: Biosynth

Chemical properties

• Molecular weight: 455.47 g/mol
• Formula: C₁₆H₁₇N₅O₇S₂
• Purity: Min. 90 Area-%
• Color/Form: White Powder