4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile
CAS: 675126-26-8
Ref. 3D-ACB12626
| 25g | To inquire | ||
| 50g | To inquire | ||
| 100g | To inquire |
Product Information
- 2-Amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile
- 2-Nitro-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile
- 2-Nitro-4-methoxy-5-[3-(morpholin-4-yl)]propoxybenzonitrile
- 4-Methoxy-5-[3-(4-morpholinyl)propoxy]-2-nitrobenzonitrile
- Gefitinib Intermediate 1
4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile is a synthetic intermediate for the synthesis of gefitinib, an anticancer medicine that is used to treat non-small cell lung cancer. The compound reacts with chloro-, 3-chloro-4-fluoroaniline and benzamide in the presence of phosphoric acid to produce the desired product. The reaction proceeds through a transfer hydrogenation mechanism, which is catalyzed by palladium chloride. This process produces 4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile at high yield and with excellent purity. It has been shown that the reaction intermediates can be salified with hydrochloric acid or hydrobromic acid to form a stable salt.
Chemical properties
Technical inquiry about: 3D-ACB12626 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
