Product Information
2-Bromo-1-(thien-2-yl)propan-1-one is a metabolite of the drug thiabendazole. It is an inhibitor of sphingomyelinase, which is an enzyme that catalyzes the hydrolysis of phospholipids to produce phosphatidic acid and sphingosine. 2-Bromo-1-(thien-2-yl)propan-1-one has been shown to inhibit the biosynthesis of sphingomyelinase in liver microsomes and also inhibits the activity of this enzyme in a pharmacophore model. This compound has been found to have inhibitory potency against sphingomyelinase in plasma samples from patients with cancer and neurological disorders.
Chemical properties
Technical inquiry about: 3D-ADA81546 2-Bromo-1-(thien-2-yl)propan-1-one
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