β-D-Glucopyranosyl taraxinic ester

CAS: 75911-14-7

Ref. 3D-ADA91114

Product Information

• Name: β-D-Glucopyranosyl taraxinic ester
• Synonyms: β-D-Glucopyranose, 1-[(3aS,6Z,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxocyclodeca[b]furan-6-carboxylate], 14-O-β-D-Glucosyltaraxinic acid, Taraxinic acid β-D-glucopyranosyl ester, Taraxinic acid β-glucopyranosyl ester, Cyclodeca[b]furan-6-carboxylic acid, 2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxo-, β-D-glucopyranosyl ester, (3aS,6Z,10E,11aR)-

Description

β-D-Glucopyranosyl taraxinic ester is a cytotoxic natural product that has been shown to inhibit the growth of tumor cells in vitro. β-D-Glucopyranosyl taraxinic ester inhibits the synthesis of nucleic acids, proteins, and lipids. It also inhibits the proliferation of lymphoid cells in vitro. The IC50 values for β-D-glucopyranosyl taraxinic ester are 0.04 mM for mouse tumor cells and 0.07 mM for human tumor cells.
β-D-Glucopyranosyl taraxinic ester has been shown to inhibit the growth of tumor cell lines in vitro, such as K562 and P388 leukemia cell lines, HeLa cervical carcinoma, and A549 lung carcinoma cell lines. This compound induces apoptosis by increasing caspase activity and decreasing bcl2 levels in these cancer cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 424.44 g/mol
• Formula: C₂₁H₂₈O₉
• Purity: Min. 95%