Product Information
- (1R,6R)-2-(6-Chloro-3-pyridinyl)-9-azabicyclo[4.2.1]non-2-ene
- 9-Azabicyclo[4.2.1]non-2-ene, 2-(6-chloro-3-pyridinyl)-, (1R)-
- 9-Azabicyclo[4.2.1]non-2-ene, 2-(6-chloro-3-pyridinyl)-, (1R,6R)-
- UB 165
Ub 165 fumarate is an inhibitor of tumor proliferation. It has been shown to inhibit the growth of tumors in mice by inhibiting the production of flavanones, which are involved in tissue differentiation and cell growth. Ub 165 fumarate also inhibits retinopathy in a rat model by blocking the action of phosphodiesterase 4 (PDE4) enzyme. This drug was also found to be toxic for a variety of human cancer cells lines, including lung, prostate, colon, breast, and leukemia cells. The mechanism behind this activity is not yet understood and may involve inhibition of cyclin-dependent kinases or other downstream targets.
Chemical properties
Technical inquiry about: 3D-AIA43286 Ub 165 fumarate
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