Product Information
PDK1 inhibitor II is a small molecule that blocks the PDK1 enzyme, which is a regulator of cellular metabolism. This compound inhibits cell growth in cancer cells and has been shown to inhibit tumor development in mice by inducing mitochondrial membrane potential collapse. This drug also has an anti-inflammatory effect and can be used as a chemotherapeutic agent for the treatment of cancers. PDK1 inhibitor II stabilizes the plasma membrane by preventing the release of phospholipids from the inner leaflet to the outer leaflet, inhibiting cell growth. The molecular weight of this molecule is 816 Da, and it has a hydrogen bond donor at position 4 and an acceptor at position 5. PDK1 inhibitor II binds to collagen with high affinity and is metabolized by esterases in plasma, liver, and kidney tissue.
Chemical properties
Technical inquiry about: 3D-AJB71764 PDK1 Inhibitor II
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