Product Information
2-Iodo-4-nitrobenzonitrile is a linker that can be used to optimize pharmacological and biological properties of the ligand. The trifluoromethyl group of 2-iodo-4-nitrobenzonitrile is a potent antagonist for the receptor with high affinity. It has been used in assays to examine the activity of ligands. 2-Iodo-4-nitrobenzonitrile can be synthesized by adding N,N'-dicyclohexylcarbodiimide (DCC) to 2,6-dichlorobenzonitrile in the presence of triethylamine (TEA). This compound is hydrophobic and can be used as a molecular model for optimization studies. 2-Iodo-4-nitrobenzonitrile has also been shown to inhibit CCR1 chemokine receptors, which are involved in inflammatory responses and development of atheros
Chemical properties
Technical inquiry about: 3D-AMA62743 2-Iodo-4-nitrobenzonitrile
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