Product Information
Ob-1 is a small molecule that inhibits the protein Stoml3, which is a component of the voltage-gated potassium channel in neurons. It does not inhibit the sodium or calcium channels. Ob-1 has been shown to attenuate nerve injury induced by sensitizing agents such as capsaicin and formalin, as well as inhibiting diabetic neuropathy in mice. The mechanism of action for this drug is unknown, but it has been detected in nerve tissue and may be involved in pathological processes such as chronic inflammation or axonal degeneration. Ob-1 also reversibly inhibits ion channels activated by nerve injury.
Chemical properties
Technical inquiry about: 3D-AMA80369 Stoml3 inhibitor ob-1
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