Product Information
The t-1101 Tosylate is a prodrug that undergoes enzymatic conversion to the active drug, t-1101. This compound induces apoptotic cell death in tumor cells and is expressed at higher levels in cancer cells than in normal tissues. It has been shown to induce apoptosis in tumor xenografts of human cardiac tissue and tumors of human breast cancer cells by binding to the protein-protein interaction site on the caspase 8 enzyme. T-1101 Tosylate is not orally bioavailable but can be administered intravenously or intraperitoneally. The t-1101 Tosylate has been shown to have synergistic effects when combined with sorafenib, a drug used for cancer therapy, which increased its potency against tumor cells.
Chemical properties
Technical inquiry about: 3D-AQD40495 t-1101 Tosylate
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