Product Information
- (R)-7-Chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide
- Benzo[b]thiophene-2-carboxamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-7-chloro-
- N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-7-chlorobenzo[b]thiophene-2-carboxamide
- Encenicline
- EVP 6124
Encenicline is a nicotinic acetylcholine receptor agonist that has been shown to improve cognition and ameliorate symptoms of schizophrenia in a randomized, double-blind, placebo-controlled trial. Encenicline binds to the α7 nicotinic acetylcholine receptor and mimics the effect of acetylcholine by stimulating postsynaptic cells in the brain. Encenicline is also under investigation as a potential biomarker for pharmacological agents that affect cognitive function. These properties may be due to its ability to cross the blood-brain barrier and stimulate postsynaptic cells in the brain. Encenicline has good oral bioavailability and low plasma protein binding, which enables it to reach therapeutic concentrations quickly.
Chemical properties
Technical inquiry about: 3D-AXA99975 encenicline
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