Product Information
- 1,4-Di(2-chloroethyl)piperazine
- Brn 0108239
- N,N'-Bis(2-chloroethyl)piperazine
- Piperazine, 1,4-bis(2-chloroethyl)-
Cyclophosphamide is a cytostatic drug that inhibits the synthesis of DNA, RNA, and protein in rapidly dividing cells. It is used for the treatment of malignant diseases such as bladder cancer and leukemia. The mutagenic activity of cyclophosphamide has been shown in rat liver cells, which may be due to its ability to bind to DNA bases and form adducts with guanine or adenine. Cyclophosphamide has also been shown to inhibit the production of urinary metabolites by rats with bladder cancer. This drug binds to DNA at a site different from its alkylating activity site, which may be responsible for its cytostatic activities.
Chemical properties
Technical inquiry about: 3D-BAA00985 1,4-Bis(2-chloroethyl)piperazine
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