1-(5-Acetyl-2,6-dimethyl-1,4-dihydropyridin-3-yl)ethan-1-one
CAS: 1079-95-4
Ref. 3D-BAA07995
1g | Discontinued | ||
25mg | Discontinued | ||
50mg | Discontinued | ||
100mg | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
- 3,5-Diacetyl-1,4-Dihydrolutidine
- 3,5-Diacetyl-1,4-Dihydro-2,6-Dimethylpyridine
- 1,1'-(2,4-Dimethyl-1,4-Dihydropyridine-3,5-Diyl)Diethanone
- 1,1'-(1,2-Dimethyl-1,4-Dihydropyridine-3,5-Diyl)Diethanone
1-Acetyl-2,6-dimethyl-1,4-dihydropyridin-3-one is a fluorescent derivative that is used in analytical chemistry. It is prepared by treating the acetyl derivative of 2,6-dimethylaniline with carbon disulphide and acetaldehyde in an alkaline solution. 1-(5-Acetyl-2,6-dimethyl-1,4-dihydropyridin-3-yl)ethanone has been shown to have high fluorescence intensity when exposed to human serum and can be used to measure uptake of drugs into cells. Fluorescent derivatives are also used in biodiesel as nonpolar solvents and flow systems for chromatography. The reaction mechanism involves the conversion of a ketone to an alcohol by addition of formaldehyde followed by oxidation of the alcohol back to a ketone using sodium hypochlorite or hydrogen peroxide.