N-Phenylmethanesulfonamide
CAS: 1197-22-4
Ref. 3D-BAA19722
| 5g | To inquire | ||
| 10g | To inquire | ||
| 25g | To inquire | ||
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| 100g | To inquire |
Product Information
- Mesylanilide
- Methanesulfanilide
- Methanesulfonamide, N-phenyl-
- Methanesulfonanilide
- Methylsulfonanilide
- N-(Methylsulfonyl)aniline
- N-Mesylaniline
- N-Methylsulphonylaniline
- N-Phenyl-Methanesulfonamid
- NSC 11329
- See more synonyms
- Timtec-Bb Sbb008328
N-Phenylmethanesulfonamide is a small-molecule drug that belongs to the class of dofetilide. It has been shown to hyperpolarize cell membranes, which can be used for the treatment of cardiac arrhythmias. Dofetilide has also been shown to have an antirheumatic effect in a model system, which may be due to its ability to inhibit the production of prostaglandins and cytokines. N-Phenylmethanesulfonamide is an ion channel blocker that blocks voltage-gated sodium channels and calcium channels, thereby reducing the release of calcium from intracellular stores. This results in membrane hyperpolarization and relaxation of cardiac muscle cells (i.e., myocytes). N-Phenylmethanesulfonamide also shows anti-inflammatory properties due to its inhibition of inflammatory mediators such as histamine, leukotrienes, and prostagland
Chemical properties
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