Product Information
2-Acetamidothiophene-3-carboxylic acid is a ligand that binds to the active site of β-lactamase, an enzyme that degrades penicillin and related antibiotics. It has been shown to bind to the catalytic site of β-lactamase with high affinity and has been used in experiments to identify inhibitors of β-lactamase. The binding constants for 2-acetamidothiophene-3-carboxylic acid have been determined experimentally using experimental data from a variety of sources including equilibrium constants, inhibition constants, and descriptors. 2-Acetamidothiophene-3-carboxylic acid binds to the active site by electrostatic interactions with the amino acids Serine and Threonine.
Chemical properties
Technical inquiry about: 3D-BCA41938 2-Acetamidothiophene-3-carboxylic acid
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