Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone
CAS: 1926163-59-8
Ref. 3D-BCD16359
| 1mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire |
Product Information
Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone is an inhibitor of the IL-2 receptor, which is a membrane protein that is involved in the activation of T lymphocytes. It has been shown to inhibit the proliferation of HL60 cells by inducing mitochondrial membrane depolarization and neuronal death. Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone also inhibits the activity of mitochondrial enzymes and induces apoptosis by downregulating proapoptotic proteins. The drug has been tested in vivo in a bowel disease model and has shown to be safe for use in pregnant animals.
Chemical properties
Technical inquiry about: 3D-BCD16359 Z-Ile-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone
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