Mifobate

CAS: 76541-72-5

Ref. 3D-BDA54172

Product Information

• Name: Mifobate
• Synonyms: (4-Chlorophenyl)(dimethoxyphosphinyl)methyl phosphoric acid dimethyl ester, Brn 5985350, Clenicor, Dimethyl (p-chloro-alpha-hydroxybenzyl)phosphonate, dimethyl phosphate, Dimethyl alpha-(dimethoxyphosphinyl)-p-chlorobenzyl phosphate, Dimethyl {(4-Chlorophenyl)[(Dimethoxyphosphoryl)Oxy]Methyl}Phosphonate, Mifobate [USAN:INN], Mifobato, Mifobato [Spanish], Mifobatum, Mifobatum [Latin], Phosphoric acid, (4-chlorophenyl)(dimethoxyphosphinyl)methyl dimethyl ester, Sr 202, Unii-Zka4Ovv12E
• CAS: 76541-72-5

Description

Mifobate is a fatty acid that is structurally similar to prostaglandin E2. It has been shown to inhibit the activation of caspase-1 and increase mitochondrial membrane potential in cells with oxidative injury. It also reduces insulin sensitivity in wild-type mice but not in transgenic animals. Mifobate can be used as a pharmaceutical dosage for the treatment of obesity, type 2 diabetes, and metabolic syndrome. Mifobate binds to Toll-like receptor 4 (TLR4) on human monocytes and inhibits peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC1α) activity. This inhibition leads to reduced insulin sensitivity and increased fatty acid release from adipose tissue.

• Brand: Biosynth

Chemical properties

• Molecular weight: 358.65 g/mol
• Formula: C₁₁H₁₇ClO₇P₂
• Purity: Min. 95%