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SR 12813
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SR 12813

CAS: 126411-39-0

Ref. 3D-BFA41139

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Estimated delivery in United States, on Wednesday 26 Jun 2024

Product Information

Name:
SR 12813
Synonyms:
  • Gw 485801
  • P,P,P′,P′-Tetraethyl P,P′-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis[phosphonate]
  • Phosphonic acid, P,P'-[2-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, tetraethyl ester
  • Phosphonic acid, P,P′-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, P,P,P′,P′-tetraethyl ester
  • Phosphonic acid, [[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, tetraethyl ester
  • Sr 12813
Description:

SR 12813 is a drug that inhibits the activity of p-glycoprotein (P-gp) and other drug transporters. It has been shown to inhibit the expression of P-gp in hepatocyte-like cells, which makes it a potential therapeutic agent for cancer patients with bowel diseases. SR 12813 also has a high affinity for polymerase chain reaction (PCR) amplification and shows synergistic effects with taxol in mouse monoclonal antibody models. The molecular mechanism of SR 12813 is not yet known, but it may be an ubiquitin ligase or a toll-like receptor inhibitor.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
504.53 g/mol
Formula:
C24H42O7P2
Purity:
Min. 95%
MDL:
Melting point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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