Product Information
GW 6471 is a small molecule that inhibits the ATP-binding cassette transporter, which is involved in the uptake of glucose and other nutrients. GW 6471 has been shown to inhibit cancer cells by reducing their energy metabolism and inhibiting mitochondrial membrane potential. It also induces apoptosis of 3T3-L1 preadipocytes by activating signal pathways involving growth factor-β1 and PPARα. This drug also has anti-inflammatory properties in an experimental model using mouse heart tissue. GW 6471 is being developed as a treatment for bowel disease and congestive heart failure.
Chemical properties
Technical inquiry about: 3D-BG179308 GW 6471
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