Product Information
- 3'-Sulfogalactosylceramide
- N-[(1S,2R,3E)-2-Hydroxy-1-[[(3-O-sulfo-β-<span class="text-smallcaps">D</span>-galactopyranosyl)oxy]methyl]-3-heptadecen-1-yl]tetracosanamide
- N-[(1S,2R,3E)-2-hydroxy-1-{[(3-O-sulfo-beta-D-galactopyranosyl)oxy]methyl}heptadec-3-en-1-yl]tetracosanamide
- Sulfatide
- Tetracosanamide, N-((1S,2R,3E)-2-hydroxy-1-(((3-O-sulfo-beta-D-galactopyranosyl)oxy)methyl)-3-heptadecenyl)-
- Tetracosanamide, N-[(1S,2R,3E)-2-hydroxy-1-[[(3-O-sulfo-β-<span class="text-smallcaps">D</span>-galactopyranosyl)oxy]methyl]-3-heptadecen-1-yl]-
- Tetracosanamide, N-[(1S,2R,3E)-2-hydroxy-1-[[(3-O-sulfo-β-<span class="text-smallcaps">D</span>-galactopyranosyl)oxy]methyl]-3-heptadecenyl]-
- Tetracosanamide, N-[2-hydroxy-1-[[(3-O-sulfo-β-<span class="text-smallcaps">D</span>-galactopyranosyl)oxy]methyl]-3-heptadecenyl]-, [R-[R*,S*-(E)]]-
Tetracosanoyl-sulfatide is a synthetic lipid molecule that has been shown to have an effect on the kinase signaling pathways of the human intestine. In particular, it binds to galactose and sulfatide in the outer membrane of Gram-negative bacteria, preventing them from interacting with regulatory proteins. This leads to increased inflammation and bowel disease development in animal models. Tetracosanoyl-sulfatide also has anti-inflammatory properties due to its ability to inhibit fatty acid synthesis by binding to the enzyme acylglycerol transferase. It has been shown that this lipid can be used as a potential therapeutic agent for inflammatory bowel diseases such as ulcerative colitis and Crohn's disease by decreasing pro-inflammatory signals and increasing anti-inflammatory signals.
Chemical properties
Technical inquiry about: 3D-BGA12271 Tetracosanoyl-sulfatide
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