Product Information
SB-737552 phosphate is a cell-permeable inhibitor of the potassium channel Kv1.3 with IC50 of 0.3 μM in Xenopus oocytes. SB-737552 phosphate is a small molecule that binds to the voltage sensor domain of Kv1.3 channels, blocking their activation and inhibiting the ion currents through them. This inhibition prevents depolarization of the membrane potential and subsequent initiation of action potentials, which are necessary for neuronal communication. SB-737552 phosphate is a high-purity, research tool for use in basic research on ion channels and protein interactions at the cellular level.
SB-737552 phosphate has been shown to bind to specific receptors on cells, including those found in cancerous cells or those involved in inflammation, providing it with additional pharmacological properties as an inhibitor or activator.
Chemical properties
Technical inquiry about: 3D-BGA46623 SB-737552 Phosphate
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