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Helvolic acid
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Helvolic acid

CAS: 29400-42-8

Ref. 3D-BH162732

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Estimated delivery in United States, on Thursday 27 Jun 2024

Product Information

Name:
Helvolic acid
Synonyms:
  • Fumigacin
  • (2Z)-2-[(17Z)-6,16-bis(acetyloxy)-4,8,10,14-tetramethyl-3,7-dioxogon-1-en-17-ylidene]-6-methylhept-5-enoic acid
  • (2Z)-2-[(4alpha,5alpha,6beta,8alpha,9beta,13alpha,14beta,16beta,17Z)-6,16-bis(acetyloxy)-4,8,10,14-tetramethyl-3,7-dioxogon-1-en-17-ylidene]-6-methylhept-5-enoic acid
  • (4α,6β,8α,9β,13α,14β,16β,17Z)-6,16-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
  • (Z)-6β,16β-Dihydroxy-3,7-dioxo-29-nor-8α,9β,13α,14β-dammara-1,17(20),24-trien-21-oic acid diacetate
  • 16-(Acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
  • 29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4-alpha,6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)-
  • 29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
  • Brn 3230584
  • Nsc 319943
  • See more synonyms
Description:

Helvolic acid is a cyclic peptide with potent Cox-2 inhibitory activity. It has been shown to have antimicrobial properties against bacteria and fungi and also has demonstrated efficacy in the treatment of infectious diseases, including HIV/AIDS. The mode of action of helvolic acid is not well understood, but it may be due to its ability to inhibit prostaglandin synthesis by blocking the formation of the enzyme Cox-2. This compound has also been shown to exhibit anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. Helvolic acid also exhibits a number of desirable biochemical properties, including solubility in water and methanol, stability at high temperatures, and low toxicity.

Brand:
Biosynth
Long term storage:
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Chemical properties

Purity:
Min. 95%
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Hazard Info

UN Number:
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Forbidden to fly:
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