(+)-Talarozole
CAS: 201410-66-4
Ref. 3D-BIA41066
| 1mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire | |
| 50mg | To inquire |
Product Information
Talarozole is a potent and selective inhibitor of human CYP3A4. It has been shown to inhibit the growth of inflammatory lesions in mice by inhibiting the production of inflammatory cytokines such as prostaglandin E2 (PGE2). Talarozole also inhibits the proliferation of hematopoietic cells, which are cells that produce all-trans retinoic acid (RA), a growth factor. The drug has been shown to reduce ventricular myocardial fatty acid content and increase fatty acid oxidation, which may reduce cardiac hypertrophy in rats.
Talarozole is an experimental drug that inhibits human cytochrome P450 3A4 (CYP3A4). This enzyme is responsible for metabolizing many drugs and other xenobiotics, and inhibition by talarozole may result in decreased metabolism. Talarozole has been shown to inhibit the growth of inflammatory lesions in mice by inhibiting the production of inflammatory cytok
Chemical properties
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