3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile
CAS: 276863-95-7
Ref. 3D-BLA86395
1g | Discontinued | ||
5g | Discontinued | ||
10g | Discontinued | ||
250mg | Discontinued | ||
500mg | Discontinued |
Product Information
- 1H-Indole-5-carbonitrile, 3-(4-chloro-1-oxobutyl)-
- 3-(4-chloro-1-oxobutyl)-1H-indole-5-carbonitrile
- Vilazodone Intermediate 6
- 3-(4-Chlorobutyryl)-1H-Indole-5-Carbonitrile
3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile is an intermediate in the production of Vilazodone. It is prepared through a reductive amination process, which involves the reduction of an amine with a carbonyl compound. This chemical is used as a precursor to commercially available pharmaceuticals, including Vilazodone. 3-(4-Chlorobutanoyl)-1H-indole-5-carbonitrile may be used as an intermediate in the synthesis of other pharmaceuticals and industrial chemicals. The salt formation with sodium borohydride has shown to be catalytic and leads to higher product yields than other methods. Process optimization may lead to increased yields and lower costs for this chemical.