HSV-1/2 IgM Hybrid Human Monoclonal Antibody
Ref. 3D-BM1395
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Product Information
Herpes simplex virus 1/2 (HSV-1/2) IgM hybrid human monoclonal antibody, produced in mice genetically modified to express human IgM heavy chain constant region. These antibodies are concentrated and spiked into an IgG depleted and delipidised human serum matrix which ensures that the final product is as close as possible to the natural disease state IgM positive human plasma. As part of the selection process for each antibody multiple clones were analyzed by commercially available IgM assays and the clones with the most reactivity were selected for commercialization. Testing in both ELISA and bead-based applications shows the products behave in an almost identical manner as the natural source.
Herpes simplex virus (HSV) is a family of viruses that can infect humans. There are two main types of herpes simplex virus: HSV-1 and HSV-2. Both HSV-1 and HSV-2 can be transmitted through direct contact with an infected person's saliva, sores, or genital and anal secretions. The viruses can enter the body through mucous membranes or small breaks in the skin. Once a person is infected, the virus establishes a lifelong infection, and there is currently no cure. The virus can periodically reactivate, leading to the recurrence of symptoms, although some infected individuals may remain asymptomatic.
Characterized disease state sera are critical components in the development and manufacture of diagnostic tests. However, sourcing of these sera is complicated, time-consuming, and sometimes suitable material is not available at all. Cymit Quimica provide monoclonal antibodies which are highly specific, reliably sourced, are produced under ISO 13485 and show lot-to-lot consistency.
Chemical properties
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