Mumps Virus IgM Hybrid Human Monoclonal Antibody
Ref. 3D-BM1401
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Product Information
The mumps virus is a member of the Paramyxoviridae family and is responsible for causing the contagious viral infection known as mumps. The virus primarily affects the salivary glands, leading to swelling and inflammation. Mumps is characterized by symptoms such as fever, headache, muscle aches, and swollen salivary glands, especially the parotid glands. Mumps is typically spread through respiratory droplets from an infected person. It can also be transmitted by touching surfaces or objects with the virus on them and then touching the face, especially the mouth or nose. While most cases of mumps are mild and self-limiting, complications can occur. These may include inflammation of other organs, such as the testicles in males or the ovaries (oophoritis) in females. Rarely, mumps can lead to more serious complications, such as meningitis or encephalitis.
Characterized disease state sera are critical components in the development and manufacture of diagnostic tests. However, sourcing of these sera is complicated, time-consuming, and sometimes suitable material is not available at all. Our Mumps Virus IgM Hybrid Human Monoclonal Antibody is reliably sourced, high specific, has lot-to-lot consistency and is produced under ISO 13485. This antibody is produced in mice genetically modified to express human IgM heavy chain constant region. They are then concentrated and spiked into an IgG depleted and delipidised human serum matrix which ensures that the final product is as close as possible to the natural disease state IgM positive human plasma. As part of the selection process for each antibody multiple clones were analyzed by commercially available IgM assays and the clones with the most reactivity were selected for commercialization. Testing in both ELISA and bead-based applications shows the products behave in an almost identical manner as the natural source.
Chemical properties
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