VZV IgM Hybrid Human Monoclonal Antibody
Ref. 3D-BM1407
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Product Information
This Varicella-Zoster Virus (VZV) IgM Hybrid Human Monoclonal Antibody is a highly specific and reliably sourced monoclonal antibody produced under ISO 13485 and with lot-to-lot consistency. Characterized disease state sera are critical components in the development and manufacture of diagnostic tests. However, sourcing of these sera is complicated, time-consuming, and sometimes suitable material is not available at all.
Cymit Quimica's VZV IgM Hybrid Human Monoclonal Antibody is produced in mice genetically modified to express human IgM heavy chain constant region. They are then concentrated and spiked into an IgG depleted and delipidised human serum matrix which ensures that the final product is as close as possible to the natural disease state IgM positive human plasma. As part of the selection process for each antibody multiple clones were analysed by commercially available IgM assays and the clones with the most reactivity were selected for commercialization. Testing in both ELISA and bead-based applications shows the products behave in an almost identical manner as the natural source.
Varicella-Zoster Virus is a member of the herpesvirus family and is responsible for causing two distinct diseases: chickenpox (varicella) and shingles (herpes zoster). Chickenpox (Varicella) is a highly contagious viral infection that primarily affects children. It is characterized by an itchy skin rash with red spots and blisters. Chickenpox is typically a mild and self-limiting illness in healthy individuals, but it can cause more severe complications in certain populations, such as newborns, pregnant women, and individuals with weakened immune systems. After a person has had chickenpox, the varicella-zoster virus remains dormant in the nerve cells. In some cases, the virus can reactivate later in life, causing a painful rash known as shingles. Shingles is characterized by a localized, often one-sided, rash and is associated with symptoms such as pain, itching, and fever. It most commonly occurs in older adults, especially those with weakened immune systems.
Chemical properties
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