Product Information
PF 846 is a research tool that was developed for use in cell biology, pharmacology, and ion channel ligand binding assays. It is an inhibitor of the Kv1.3 voltage-gated potassium channel, which is expressed in cardiac cells and neurons. PF 846 has been shown to inhibit L-type calcium channels and alpha-2A adrenergic receptors as well. PF 846 binds to the peptide receptor site of these channels, blocking the passage of ions or neurotransmitters. The high purity and high specificity of this compound make it useful for research applications in protein interactions and antibody generation.
Chemical properties
Technical inquiry about: 3D-BP177454 PF 846
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