Product Information
4-Bromo-N-ethylphthalimide is a drug that belongs to the group of topoisomerase inhibitors. It has been shown to be an active form of anthracene and has catalytic activity against DNA gyrase. The compound has been optimized by crystallization with dihedral angles, which allows for its use in biological research. 4-Bromo-N-ethylphthalimide binds to the active site of bacterial topoisomerases I and II and prevents the enzymes from relaxing supercoiled DNA. This leads to an accumulation of DNA double helices, which may lead to cell death.
Chemical properties
Technical inquiry about: 3D-BPA99219 4-Bromo-N-ethylphthalimide
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