Estimated delivery in United States, on Friday 12 Jul 2024
Product Information
Name:
WM 1119
CAS:
Description:
Selective and potent inhibitor of lysine acetyltransferases KAT6A and KAT6B with IC50 values in low nanomolar range. The compound is a reversible competitor of acetyl coenzyme A domain of KAT6A/B enzymes. It inhibits MYST-catalysed histone acetylation and was shown to arrest lymphoma progression in mice models. The compound opened the door to a new class of cancer therapeutics that could potentially direct the cancer cells in senescence or permanent dormancy.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
389.38 g/mol
Formula:
C18H13F2N3O3S
Purity:
Min. 95%
Color/Form:
White/Off-White Solid
InChI:
InChI=1S/C18H13F2N3O3S/c19-14-10-12(16-6-3-4-8-21-16)9-13(11-14)18(24)22-23-27(25,26)17-7-2-1-5-15(17)20/h1-11,23H,(H,22,24)
InChI key:
InChIKey=QLXULUNLCRKWRD-UHFFFAOYSA-N
SMILES:
O=C(NNS(=O)(=O)c1ccccc1F)c1cc(F)cc(-c2ccccn2)c1
MDL:
Melting point:
Boiling point:
Flash point:
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Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: 3D-BW166843 WM 1119
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