(β)-1-D-Ribofuranosyl-3-guanylurea

CAS: 2508-80-7

Ref. 3D-CAA50880

Product Information

• Name: (β)-1-D-Ribofuranosyl-3-guanylurea
• Synonyms: 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-3-guanylurea, N-(Aminoiminomethyl)-N′-β-<span class="text-smallcaps">D</span>-ribofuranosylurea, N-[(diaminomethylidene)carbamoyl]pentofuranosylamine, NSC 264412, Urea, 1-(diaminomethylene)-3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, Urea, 1-amidino-3-β-<span class="text-smallcaps">D</span>-ribofuranosyl-, Urea, N-(aminoiminomethyl)-N′-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• CAS: 2508-80-7

Description

(β)-1-D-Ribofuranosyl-3-guanylurea is a deaminase inhibitor that prevents the conversion of cytidine to uracil by inhibiting the enzyme cytidine deaminase. It has been used in the encapsulation of cyclopentyl and 5-azacytidine, which are compounds that inhibit DNA synthesis and have antiviral properties. This active form is also an antisolvent with a ring-opening mechanism, which has shown activity against viruses. (β)-1-D-Ribofuranosyl-3-guanylurea can be used in flow systems with chloride or diode detectors for kinetic studies. The use of this compound in supercritical fluid chromatography is limited due to its low solubility in CO2.

• Brand: Biosynth

Chemical properties

• Molecular weight: 234.21 g/mol
• Formula: C₇H₁₄N₄O₅
• Purity: Min. 95%