Picraline
CAS: 2671-32-1
Ref. 3D-CAA67132
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Product Information
- 2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylicacid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-14-(hydroxymethyl)-, methyl ester,acetate (7CI)
- Akuammilan-16-carboxylic acid,17-(acetyloxy)-2,5-epoxy-1,2-dihydro-, methyl ester, (2a,5a,16R)-
- 2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid,14-[(acetyloxy)methyl]-3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester,[2S-(2a,3E,6b,7aa,12ab,12bb,14S*)]-
Picraline is an indole alkaloid that inhibits uptake of compounds by the cell. It is a potent inhibitor of sodium potassium-ATPase. Picraline has significant cytotoxicity and, in particular, causes a tail-flick response in mice. This drug also has antinociceptive properties and has been shown to have some analgesic effects in mice. The hydrochloride salt of picraline is made by reacting picraline with hydrochloric acid and then crystallizing the product from water with sodium carbonate. Picraline can be used as an antigen for immunohistochemical staining of gliomas, which are tumors that arise from the glial cells of the central nervous system. The structural formula for picraline can be seen below:
C8H8N2O2
The chemical name for picraline is 1-(3-indolyl)-1-pentanone.br>
Picral
Chemical properties
Technical inquiry about: 3D-CAA67132 Picraline
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