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2-Oxo-1-oxaspiro[4.5]decane-4-carboxylic acid
CAS: 2819-56-9
Ref. 3D-CAA81956
| 250mg | 302.00 € | ||
| 2500mg | 1,131.00 € |
Product Information
- 1-Oxaspiro[4.5]decane-4-carboxylic acid, 2-oxo-
- Butanedioic acid, (1-hydroxycyclohexyl)-, γ-lactone
- Cyclohexanesuccinic acid, 1-hydroxy-, γ-lactone
- NSC 25328
2-Oxo-1-oxaspiro[4.5]decane-4-carboxylic acid is a nitrile that can be synthesized by decarboxylation of 4-chloro-2,6-dimethylaniline with nitrous acid and sulfuric acid. The intramolecular cyclization of methyl 2-(nitrobenzyl)malonate to the thiazole ring is catalyzed by a mixture of acetic anhydride and pyridine. The reaction is carried out at refluxing temperatures in a homogeneous solvent such as toluene or chloroform. This product can also be obtained from the reaction of 2,6-dimethylaniline with hydroxylamine hydrochloride in the presence of sodium hydroxide.
Chemical properties
Technical inquiry about: 3D-CAA81956 2-Oxo-1-oxaspiro[4.5]decane-4-carboxylic acid
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